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Brain Kynurenine Pathway Metabolite Levels May Reflect Extent of Neuroinflammation in ALS, FTD and Early Onset AD

Objectives: Despite distinct clinical profiles, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) patients share a remarkable portion of pathological features, with a substantial percentage of patients displaying a mixed disease phenotype. Kynurenine metabolism seems to play a ro...

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Detalles Bibliográficos
Autores principales: Heylen, Annelies, Vermeiren, Yannick, Kema, Ido P., van Faassen, Martijn, van der Ley, Claude, Van Dam, Debby, De Deyn, Peter P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143579/
https://www.ncbi.nlm.nih.gov/pubmed/37111372
http://dx.doi.org/10.3390/ph16040615