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In Silico Analyses of a Promising Drug Candidate for the Treatment of Amyotrophic Lateral Sclerosis Targeting Superoxide Dismutase I Protein

Amyotrophic lateral sclerosis (ALS) is the most prevalent motor neuron disorder in adults, which is associated with a highly disabling condition. To date, ALS remains incurable, and the only drugs approved by the FDA for its treatment confer a limited survival benefit. Recently, SOD1 binding ligand...

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Detalles Bibliográficos
Autores principales: Pereira, Gabriel Rodrigues Coutinho, Abrahim-Vieira, Bárbara de Azevedo, de Mesquita, Joelma Freire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143751/
https://www.ncbi.nlm.nih.gov/pubmed/37111580
http://dx.doi.org/10.3390/pharmaceutics15041095