The Uremic Toxin Indoxyl Sulfate Accelerates Senescence in Kidney Proximal Tubule Cells

Kidney fibrosis is the common final pathway of nearly all chronic and progressive nephropathies. One cause may be the accumulation of senescent cells that secrete factors (senescence associated secretory phenotype, SASP) promoting fibrosis and inflammation. It has been suggested that uremic toxins,...

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Detalles Bibliográficos
Autores principales: Yang, Yi, Mihajlovic, Milos, Janssen, Manoe J., Masereeuw, Rosalinde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143766/
https://www.ncbi.nlm.nih.gov/pubmed/37104179
http://dx.doi.org/10.3390/toxins15040242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143766/
https://www.ncbi.nlm.nih.gov/pubmed/37104179
http://dx.doi.org/10.3390/toxins15040242

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