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Bacterial Production of Recombinant Coagulation Factor VIII Domains
Factor VIII (F8) is a blood coagulation protein prearranged in six domains, and its deficiency causes hemophilia A. To fashion functional F8 therapeutics, development of a recombinant F8 (rF8) domain is essential not only for F8 substitution, but also to decipher the F8-related mechanisms. In this s...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143837/ https://www.ncbi.nlm.nih.gov/pubmed/37109652 http://dx.doi.org/10.3390/medicina59040694 |