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Bacterial Production of Recombinant Coagulation Factor VIII Domains

Factor VIII (F8) is a blood coagulation protein prearranged in six domains, and its deficiency causes hemophilia A. To fashion functional F8 therapeutics, development of a recombinant F8 (rF8) domain is essential not only for F8 substitution, but also to decipher the F8-related mechanisms. In this s...

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Detalles Bibliográficos
Autores principales: Bashar, Saima, Jeong, Hee-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143837/
https://www.ncbi.nlm.nih.gov/pubmed/37109652
http://dx.doi.org/10.3390/medicina59040694