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The Replicative DnaE Polymerase of Bacillus subtilis Recruits the Glycolytic Pyruvate Kinase (PykA) When Bound to Primed DNA Templates

The glycolytic enzyme PykA has been reported to drive the metabolic control of replication through a mechanism involving PykA moonlighting functions on the essential DnaE polymerase, the DnaC helicase and regulatory determinants of PykA catalytic activity in Bacillus subtilis. The mutants of this co...

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Detalles Bibliográficos
Autores principales: Holland, Alexandria, Pitoulias, Matthaios, Soultanas, Panos, Janniere, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143966/
https://www.ncbi.nlm.nih.gov/pubmed/37109494
http://dx.doi.org/10.3390/life13040965