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The Interaction Mechanism of Intramuscular Gene Delivery Materials with Cell Membranes

It has been confirmed that skeletal muscle cells have the capability to receive foreign plasmid DNA (pDNA) and express functional proteins. This provides a promisingly applicable strategy for safe, convenient, and economical gene therapy. However, intramuscular pDNA delivery efficiency was not high...

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Detalles Bibliográficos
Autores principales: Cui, Zhanpeng, Jiao, Yang, Pu, Linyu, Chen, Jianlin, Liu, Ming, Tang, James Zhenggui, Wang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10144004/
https://www.ncbi.nlm.nih.gov/pubmed/37103309
http://dx.doi.org/10.3390/jfb14040219