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New Hybrid Scaffolds Based on 5-FU/Curcumin: Synthesis, Cytotoxic, Antiproliferative and Pro-Apoptotic Effect

A series of 5-FU-Curcumin hybrids were synthesized, and their structures were elucidated by spectroscopic analysis. The synthesized hybrid compounds were evaluated in different colorectal cancer cell lines (SW480 and SW620) and in non-malignant cells (HaCaT and CHO-K1), to determine their chemopreve...

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Detalles Bibliográficos
Autores principales: Moreno-Quintero, Gustavo, Betancur-Zapata, Emmanuel, Herrera-Ramírez, Angie, Cardona-Galeano, Wilson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10144058/
https://www.ncbi.nlm.nih.gov/pubmed/37111708
http://dx.doi.org/10.3390/pharmaceutics15041221