Cargando…

New Hybrid Scaffolds Based on 5-FU/Curcumin: Synthesis, Cytotoxic, Antiproliferative and Pro-Apoptotic Effect

A series of 5-FU-Curcumin hybrids were synthesized, and their structures were elucidated by spectroscopic analysis. The synthesized hybrid compounds were evaluated in different colorectal cancer cell lines (SW480 and SW620) and in non-malignant cells (HaCaT and CHO-K1), to determine their chemopreve...

Descripción completa

Detalles Bibliográficos
Autores principales:	Moreno-Quintero, Gustavo, Betancur-Zapata, Emmanuel, Herrera-Ramírez, Angie, Cardona-Galeano, Wilson
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10144058/ https://www.ncbi.nlm.nih.gov/pubmed/37111708 http://dx.doi.org/10.3390/pharmaceutics15041221

Ejemplares similares

New Hybrids Based on Curcumin and Resveratrol: Synthesis, Cytotoxicity and Antiproliferative Activity against Colorectal Cancer Cells
por: Hernández, Cristian, et al.
Publicado: (2021)

Synthesis and Chemopreventive Potential of 5-FU/Genistein Hybrids on Colorectal Cancer Cells
por: Moreno-Quintero, Gustavo, et al.
Publicado: (2022)

Antiproliferative, Cytotoxic, and Apoptotic Activity of Steroidal Oximes in Cervicouterine Cell Lines
por: Sánchez-Sánchez, Luis, et al.
Publicado: (2016)

Antiproliferative and Apoptotic Effects of Graphene Oxide @AlFu MOF Based Saponin Natural Product on OSCC Line
por: Mousavi, Seyyed Mojtaba, et al.
Publicado: (2022)

Resveratrol/Hydrazone Hybrids: Synthesis and Chemopreventive Activity against Colorectal Cancer Cells
por: Castrillón-López, Wilson, et al.
Publicado: (2022)

Synergistic Effect of Garcinol and Curcumin on Antiproliferative and Apoptotic Activity in Pancreatic Cancer Cells
por: Parasramka, Mansi A., et al.
Publicado: (2012)

Synthesis of Saccharumoside-B analogue with potential of antiproliferative and pro-apoptotic activities
por: Rayavarapu, Srinuvasarao, et al.
Publicado: (2017)

Erratum to “Synergistic Effect of Garcinol and Curcumin on Antiproliferative and Apoptotic Activity in Pancreatic Cancer Cells”
por: Parasramka, Mansi A., et al.
Publicado: (2019)

Antiproliferative and pro-apoptotic activity of eugenol-related biphenyls on malignant melanoma cells
por: Pisano, Marina, et al.
Publicado: (2007)

Antiproliferative and Pro-Apoptotic Effects of MiR-4286 Inhibition in Melanoma Cells
por: Komina, Anna, et al.
Publicado: (2016)

Antiproliferative and pro-apoptotic activity of melatonin analogues on melanoma and breast cancer cells
por: Gatti, Giuliana, et al.
Publicado: (2017)

Cytotoxic, Antiproliferative and Pro-Apoptotic Effects of 5-Hydroxyl-6,7,3′,4′,5′-Pentamethoxyflavone Isolated from Lantana ukambensis
por: Sawadogo, Wamtinga Richard, et al.
Publicado: (2015)

Proapoptotic Effect and Molecular Docking Analysis of Curcumin–Resveratrol Hybrids in Colorectal Cancer Chemoprevention
por: Moreno-Q, Gustavo, et al.
Publicado: (2022)

LNO3 AND L3 Are Associated With Antiproliferative And Pro-Apoptotic Action In Hepatoma Cells
por: Zanelatto, Leonardo Campos, et al.
Publicado: (2016)

Publisher Correction: Synthesis of Saccharumoside-B analogue with potential of antiproliferative and pro-apoptotic activities
por: Rayavarapu, Srinuvasarao, et al.
Publicado: (2020)

Antiproliferative and pro-apoptotic effects afforded by novel Src-kinase inhibitors in human neuroblastoma cells
por: Navarra, Michele, et al.
Publicado: (2010)

Antiproliferative and Pro-Apoptotic Effect of Novel Nitro-Substituted Hydroxynaphthanilides on Human Cancer Cell Lines
por: Kauerova, Tereza, et al.
Publicado: (2016)

Antiproliferative and apoptotic effects of spanish honeys
por: Morales, Paloma, et al.
Publicado: (2013)

Antiproliferative and apoptotic effects of xanthohumol in cholangiocarcinoma
por: Walden, Daniel, et al.
Publicado: (2017)

Targeting multiple pro-apoptotic signaling pathways with curcumin in prostate cancer cells
por: Rivera, Mariela, et al.
Publicado: (2017)

Dodonaea viscosa Jacq. induces cytotoxicity, antiproliferative activity, and cell death in colorectal cancer cells via regulation of caspase 3 and p53
por: Herrera-Calderon, Oscar, et al.
Publicado: (2023)

Synthesis and in Vitro Cytotoxic Activity of Compounds with Pro-Apoptotic Potential
por: Soares, Giselle Apicela, et al.
Publicado: (2009)

Phytochemical Characterization of Taxus baccata L. Aril with Emphasis on Evaluation of the Antiproliferative and Pro-Apoptotic Activity of Rhodoxanthin
por: Dumitraş, Daria-Antonia, et al.
Publicado: (2022)

Resveratrol, Epigallocatechin Gallate and Curcumin for Cancer Therapy: Challenges from Their Pro-Apoptotic Properties
por: Chimento, Adele, et al.
Publicado: (2023)

The antiproliferative and apoptotic profile of gomesin against DFTD
por: Ikonomopoulou, Maria P., et al.
Publicado: (2018)

Pro-apoptotic and antiproliferative activity of human KCNRG, a putative tumor suppressor in 13q14 region
por: Birerdinc, Aybike, et al.
Publicado: (2009)

Novel Acylguanidine Derivatives Targeting Smoothened Induce Antiproliferative and Pro-Apoptotic Effects in Chronic Myeloid Leukemia Cells
por: Chiarenza, Alessandra, et al.
Publicado: (2016)

Bromodomain-containing protein 4 is critical for the antiproliferative and pro-apoptotic effects of gambogic acid in anaplastic thyroid cancer
por: Wang, Yonghui, et al.
Publicado: (2018)

8a, a New Acridine Antiproliferative and Pro-Apoptotic Agent Targeting HDAC1/DNMT1
por: Zhang, Qiting, et al.
Publicado: (2021)

Antiproliferative Effects of Curcumin Different Types of Breast Cancer
por: Guneydas, Goksu, et al.
Publicado: (2022)

Antiproliferative and Apoptotic Activities of the Medicinal Plant Ziziphus obtusifolia
por: Molina-Romo, Edna D., et al.
Publicado: (2018)

Antiproliferative and apoptotic effects of telmisartan in human glioma cells
por: Chang, Yung-Lung, et al.
Publicado: (2023)

Chemopreventive Effect on Human Colon Adenocarcinoma Cells of Styrylquinolines: Synthesis, Cytotoxicity, Proapoptotic Effect and Molecular Docking Analysis
por: Bedoya-Betancur, Vanesa, et al.
Publicado: (2022)

Proteomic analysis of the chemosensitizing effect of curcumin on CRC cells treated with 5-FU
por: Yang, Jingbo, et al.
Publicado: (2022)

Cytotoxic and Pro-Apoptotic Effects of Leaves Extract of Antiaris africana Engler (Moraceae)
por: Thiam, Khadidiatou, et al.
Publicado: (2022)

Antiproliferative and pro-apoptotic effects of Cyclocarya paliurus polysaccharide and X-ray irradiation combination on SW480 colorectal cancer cells
por: Jin, Yongjun, et al.
Publicado: (2019)

Tomentosin a Sesquiterpene Lactone Induces Antiproliferative and Proapoptotic Effects in Human Burkitt Lymphoma by Deregulation of Anti- and Pro-Apoptotic Genes
por: Virdis, Patrizia, et al.
Publicado: (2021)

Antiproliferative and apoptotic effects of telmisartan in human colon cancer cells
por: LEE, LUCAS D., et al.
Publicado: (2014)

Antiproliferative and Apoptotic Potential of Cyanidin-Based Anthocyanins on Melanoma Cells
por: Rugină, Dumitriţa, et al.
Publicado: (2017)

Anti-proliferative and pro-apoptotic effects of curcumin on skin cutaneous melanoma: Bioinformatics analysis and in vitro experimental studies
por: Li, Long, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_jbjmot98krarpd03riljb6rruj