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In Silico Exploration of Alternative Conformational States of VDAC

VDAC (Voltage-Dependent Anion-selective Channel) is the primary metabolite pore in the mitochondrial outer membrane (OM). Atomic structures of VDAC, consistent with its physiological “open” state, are β-barrels formed by 19 transmembrane (TM) β-strands and an N-terminal segment (NTERM) that folds in...

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Detalles Bibliográficos
Autor principal: Mannella, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10144127/
https://www.ncbi.nlm.nih.gov/pubmed/37110543
http://dx.doi.org/10.3390/molecules28083309