Synthesis and Evaluation of Novel Nitric Oxide-Donating Ligustrazine Derivatives as Potent Antiplatelet Aggregation Agents

Antiplatelet aggregation agents have demonstrated clinical benefits in the treatment of ischemic stroke. In our study, a series of novel nitric oxide (NO)-donating ligustrazine derivatives were designed and synthesized as antiplatelet aggregation agents. They were evaluated for the inhibitory effect...

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Detalles Bibliográficos
Autores principales: Li, Han-Xu, Tian, Jian-Hui, Li, Hua-Yu, Wan, Xin, Zou, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10144142/
https://www.ncbi.nlm.nih.gov/pubmed/37110589
http://dx.doi.org/10.3390/molecules28083355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10144142/
https://www.ncbi.nlm.nih.gov/pubmed/37110589
http://dx.doi.org/10.3390/molecules28083355

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