Hepatic G Protein-Coupled Receptor 180 Deficiency Ameliorates High Fat Diet-Induced Lipid Accumulation via the Gi-PKA-SREBP Pathway

Single-nucleotide polymorphisms in G protein-coupled receptor 180 (GPR180) are associated with hypertriglyceridemia. The aim of this study was to determine whether hepatic GPR180 impacts lipid metabolism. Hepatic GPR180 was knocked down using two approaches: Gpr180-specific short hairpin (sh)RNA car...

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Detalles Bibliográficos
Autores principales: Zhang, Yunhua, Zhu, Ziming, Sun, Lijun, Yin, Wenzhen, Liang, Yuan, Chen, Hong, Bi, Yanghui, Zhai, Wenbo, Yin, Yue, Zhang, Weizhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10144310/
https://www.ncbi.nlm.nih.gov/pubmed/37111058
http://dx.doi.org/10.3390/nu15081838

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10144310/
https://www.ncbi.nlm.nih.gov/pubmed/37111058
http://dx.doi.org/10.3390/nu15081838

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