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A COVID-19 DNA Vaccine Candidate Elicits Broadly Neutralizing Antibodies against Multiple SARS-CoV-2 Variants including the Currently Circulating Omicron BA.5, BF.7, BQ.1 and XBB

Waves of breakthrough infections by SARS-CoV-2 Omicron subvariants currently pose a global challenge to the control of the COVID-19 pandemic. We previously reported a pVAX1-based DNA vaccine candidate, pAD1002, that encodes a receptor-binding domain (RBD) chimera of SARS-CoV-1 and Omicron BA.1. In m...

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Detalles Bibliográficos
Autores principales: Ding, Yuan, Fan, Feng, Xu, Xin, Zhao, Gan, Zhang, Xin, Zhao, Huiyun, Wang, Limei, Wang, Bin, Gao, Xiao-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10144402/
https://www.ncbi.nlm.nih.gov/pubmed/37112691
http://dx.doi.org/10.3390/vaccines11040778