The Novel Artemisinin Dimer Isoniazide ELI-XXIII-98-2 Induces c-MYC Inhibition, DNA Damage, and Autophagy in Leukemia Cells

The proto-oncogenic transcription factor c-MYC plays a pivotal role in the development of tumorigenesis, cellular proliferation, and the control of cell death. Its expression is frequently altered in many cancer types, including hematological malignancies such as leukemia. The dimer isoniazide ELI-X...

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Detalles Bibliográficos
Autores principales: Elbadawi, Mohamed, Boulos, Joelle C., Dawood, Mona, Zhou, Min, Gul, Waseem, ElSohly, Mahmoud A., Klauck, Sabine M., Efferth, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10144546/
https://www.ncbi.nlm.nih.gov/pubmed/37111592
http://dx.doi.org/10.3390/pharmaceutics15041107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10144546/
https://www.ncbi.nlm.nih.gov/pubmed/37111592
http://dx.doi.org/10.3390/pharmaceutics15041107

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