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The Novel Artemisinin Dimer Isoniazide ELI-XXIII-98-2 Induces c-MYC Inhibition, DNA Damage, and Autophagy in Leukemia Cells
The proto-oncogenic transcription factor c-MYC plays a pivotal role in the development of tumorigenesis, cellular proliferation, and the control of cell death. Its expression is frequently altered in many cancer types, including hematological malignancies such as leukemia. The dimer isoniazide ELI-X...
Autores principales: | Elbadawi, Mohamed, Boulos, Joelle C., Dawood, Mona, Zhou, Min, Gul, Waseem, ElSohly, Mahmoud A., Klauck, Sabine M., Efferth, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10144546/ https://www.ncbi.nlm.nih.gov/pubmed/37111592 http://dx.doi.org/10.3390/pharmaceutics15041107 |
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