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Supramolecular Arrangement of Doxycycline with Sulfobutylether-β-Cyclodextrin: Impact on Nanostructuration with Chitosan, Drug Degradation and Antimicrobial Potency

Doxycycline (DX) is a well-established and broad-spectrum antimicrobial drug. However, DX has drawbacks, such as physicochemical instability in aqueous media and bacterial resistance. The inclusion of drugs in cyclodextrin complexes and their loading into nanocarriers can overcome these limitations....

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Detalles Bibliográficos
Autores principales: Carvalho Feitosa, Renata, Souza Ribeiro Costa, Juliana, van Vliet Lima, Marcelo, Sawa Akioka Ishikawa, Elina, Cogo Müller, Karina, Bonin Okasaki, Fernando, Sabadini, Edvaldo, Garnero, Claudia, Longhi, Marcela Raquel, Lavayen, Vladimir, da Silva-Júnior, Arnóbio Antônio, Oliveira-Nascimento, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10144562/
https://www.ncbi.nlm.nih.gov/pubmed/37111770
http://dx.doi.org/10.3390/pharmaceutics15041285