A Straightforward Method for the Development of Positively Charged Gold Nanoparticle-Based Vectors for Effective siRNA Delivery

The therapeutic potential of short interfering RNA (siRNA) to treat many diseases that are incurable with traditional preparations is limited by the extensive metabolism of serum nucleases, low permeability through biological membrane barriers because of a negative charge, and endosomal trapping. Ef...

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Detalles Bibliográficos
Autores principales: Elizarova, Tatiana N., Antopolsky, Maxim L., Novichikhin, Denis O., Skirda, Artemiy M., Orlov, Alexey V., Bragina, Vera A., Nikitin, Petr I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10144622/
https://www.ncbi.nlm.nih.gov/pubmed/37110552
http://dx.doi.org/10.3390/molecules28083318

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10144622/
https://www.ncbi.nlm.nih.gov/pubmed/37110552
http://dx.doi.org/10.3390/molecules28083318

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