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Codon Pair Deoptimization (CPD)-Attenuated PRRSV-1 Vaccination Exhibit Immunity to Virulent PRRSV Challenge in Pigs

Commercially used porcine respiratory and reproductive syndrome (PRRS) modified live virus (MLV) vaccines provide limited protection with heterologous viruses, can revert back to a virulent form and they tend to recombine with circulating wild-type strains. Codon pair deoptimization (CPD) is an adva...

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Detalles Bibliográficos
Autores principales: Lee, Min-A, You, Su-Hwa, Jayaramaiah, Usharani, Shin, Eun-Gyeong, Song, Seung-Min, Ju, Lanjeong, Kang, Seok-Jin, Cho, Sun Hee, Hyun, Bang-Hun, Lee, Hyang-Sim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10144691/
https://www.ncbi.nlm.nih.gov/pubmed/37112689
http://dx.doi.org/10.3390/vaccines11040777