Pseurotin A Validation as a Metastatic Castration-Resistant Prostate Cancer Recurrence-Suppressing Lead via PCSK9-LDLR Axis Modulation

Metastatic castration-resistant prostate cancer (mCRPC) cells can de novo biosynthesize their own cholesterol and overexpress proprotein convertase subtilisin/kexin type 9 (PCSK9). PCSK9 proved to contribute to mCRPC cell motility since PCSK9 knockdown (KD) in mCRPC CWR-R1ca cells led to notable red...

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Detalles Bibliográficos
Autores principales: Abdelwahed, Khaldoun S., Siddique, Abu Bakar, Ebrahim, Hassan Y., Qusa, Mohammed H., Mudhish, Ethar A., Rad, Ashkan H., Zerfaoui, Mourad, Abd Elmageed, Zakaria Y., El Sayed, Khalid A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10144979/
https://www.ncbi.nlm.nih.gov/pubmed/37103355
http://dx.doi.org/10.3390/md21040215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10144979/
https://www.ncbi.nlm.nih.gov/pubmed/37103355
http://dx.doi.org/10.3390/md21040215

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