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Identification of Anti-gp41 Monoclonal Antibodies That Effectively Target Cytotoxic Immunoconjugates to Cells Infected with Human Immunodeficiency Virus, Type 1

We are developing cytotoxic immunoconjugates (CICs) targeting the envelope protein (Env) of the Human Immunodeficiency Virus, type 1 (HIV) to purge the persistent reservoirs of viral infection. We have previously studied the ability of multiple monoclonal antibodies (mAbs) to deliver CICs to an HIV-...

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Detalles Bibliográficos
Autores principales: Klug, Grant, Cole, Frances M., Hicar, Mark D., Watt, Connie, Peters, Tami, Pincus, Seth H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10144985/
https://www.ncbi.nlm.nih.gov/pubmed/37112741
http://dx.doi.org/10.3390/vaccines11040829