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Natural Polyphenols—Resveratrol, Quercetin, Magnolol, and β-Catechin—Block Certain Aspects of Heroin Addiction and Modulate Striatal IL-6 and TNF-α

We have examined the effects of four different polyphenols in attenuating heroin addiction using a conditioned place preference (CPP) paradigm. Adult male Sprague Dawley rats received heroin (alternating with saline) in escalating doses starting from 10 mg/kg, i.p. up to 80 mg/kg/d for 14 consecutiv...

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Detalles Bibliográficos
Autores principales: ElShebiney, Shaimaa, Elgohary, Rania, El-Shamarka, Marwa, Mowaad, Noha, Abulseoud, Osama A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145039/
https://www.ncbi.nlm.nih.gov/pubmed/37112606
http://dx.doi.org/10.3390/toxics11040379