Targeted Extracellular Vesicle Gene Therapy for Modulating Alpha-Synuclein Expression in Gut and Spinal Cord

The development of effective disease-modifying therapies to halt Parkinson’s disease (PD) progression is required. In a subtype of PD patients, alpha-synuclein pathology may start in the enteric nervous system (ENS) or autonomic peripheral nervous system. Consequently, strategies to decrease the exp...

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Detalles Bibliográficos
Autores principales: Izco, Maria, Schleef, Martin, Schmeer, Marco, Carlos, Estefania, Verona, Guglielmo, Alvarez-Erviti, Lydia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145068/
https://www.ncbi.nlm.nih.gov/pubmed/37111717
http://dx.doi.org/10.3390/pharmaceutics15041230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145068/
https://www.ncbi.nlm.nih.gov/pubmed/37111717
http://dx.doi.org/10.3390/pharmaceutics15041230

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