Chemico-Physical Properties of Some 1,1′-Bis-alkyl-2,2′-hexane-1,6-diyl-bispyridinium Chlorides Hydrogenated and Partially Fluorinated for Gene Delivery

The development of very efficient and safe non-viral vectors, constituted mainly by cationic lipids bearing multiple charges, is a landmark for in vivo gene-based medicine. To understand the effect of the hydrophobic chain’s length, we here report the synthesis, and the chemico-physical and biologic...

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Detalles Bibliográficos
Autores principales: Massa, Michele, Rivara, Mirko, Pertinhez, Thelma A., Compari, Carlotta, Donofrio, Gaetano, Cristofolini, Luigi, Orsi, Davide, Franceschi, Valentina, Fisicaro, Emilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145364/
https://www.ncbi.nlm.nih.gov/pubmed/37110819
http://dx.doi.org/10.3390/molecules28083585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145364/
https://www.ncbi.nlm.nih.gov/pubmed/37110819
http://dx.doi.org/10.3390/molecules28083585

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