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Chemico-Physical Properties of Some 1,1′-Bis-alkyl-2,2′-hexane-1,6-diyl-bispyridinium Chlorides Hydrogenated and Partially Fluorinated for Gene Delivery

The development of very efficient and safe non-viral vectors, constituted mainly by cationic lipids bearing multiple charges, is a landmark for in vivo gene-based medicine. To understand the effect of the hydrophobic chain’s length, we here report the synthesis, and the chemico-physical and biologic...

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Detalles Bibliográficos
Autores principales:	Massa, Michele, Rivara, Mirko, Pertinhez, Thelma A., Compari, Carlotta, Donofrio, Gaetano, Cristofolini, Luigi, Orsi, Davide, Franceschi, Valentina, Fisicaro, Emilia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145364/ https://www.ncbi.nlm.nih.gov/pubmed/37110819 http://dx.doi.org/10.3390/molecules28083585

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