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Human Cytomegalovirus UL23 Antagonizes the Antiviral Effect of Interferon-γ by Restraining the Expression of Specific IFN-Stimulated Genes

Interferon-γ (IFN-γ) is a critical component of innate immune responses in humans to combat infection by many viruses, including human cytomegalovirus (HCMV). IFN-γ exerts its biological effects by inducing hundreds of IFN-stimulated genes (ISGs). In this study, RNA-seq analyses revealed that HCMV t...

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Detalles Bibliográficos
Autores principales: Wang, Hankun, Peng, Weijian, Wang, Jialin, Zhang, Chunling, Zhao, Wangchun, Ran, Yanhong, Yang, Xiaoping, Chen, Jun, Li, Hongjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145438/
https://www.ncbi.nlm.nih.gov/pubmed/37112994
http://dx.doi.org/10.3390/v15041014