Cargando…
Human Cytomegalovirus UL23 Antagonizes the Antiviral Effect of Interferon-γ by Restraining the Expression of Specific IFN-Stimulated Genes
Interferon-γ (IFN-γ) is a critical component of innate immune responses in humans to combat infection by many viruses, including human cytomegalovirus (HCMV). IFN-γ exerts its biological effects by inducing hundreds of IFN-stimulated genes (ISGs). In this study, RNA-seq analyses revealed that HCMV t...
Autores principales: | Wang, Hankun, Peng, Weijian, Wang, Jialin, Zhang, Chunling, Zhao, Wangchun, Ran, Yanhong, Yang, Xiaoping, Chen, Jun, Li, Hongjian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145438/ https://www.ncbi.nlm.nih.gov/pubmed/37112994 http://dx.doi.org/10.3390/v15041014 |
Ejemplares similares
-
Human cytomegalovirus UL23 inhibits transcription of interferon-γ stimulated genes and blocks antiviral interferon-γ responses by interacting with human N-myc interactor protein
por: Feng, Linyuan, et al.
Publicado: (2018) -
Human Cytomegalovirus UL23 Attenuates Signal Transducer and Activator of Transcription 1 Phosphorylation and Type I Interferon Response
por: Feng, Linyuan, et al.
Publicado: (2021) -
The Cytomegalovirus Tegument Protein UL35 Antagonizes Pattern Recognition Receptor-Mediated Type I IFN Transcription
por: Fabits, Markus, et al.
Publicado: (2020) -
Human cytomegalovirus protein UL42 antagonizes cGAS/MITA-mediated innate antiviral response
por: Fu, Yu-Zhi, et al.
Publicado: (2019) -
The Molecular Mechanism of Herpes Simplex Virus 1 UL31 in Antagonizing the Activity of IFN-β
por: Gong, Lan, et al.
Publicado: (2022)