APC Loss Prevents Doxorubicin-Induced Cell Death by Increasing Drug Efflux and a Chemoresistant Cell Population in Breast Cancer

Chemoresistance is a major health concern affecting cancer patients. Resistance is multifactorial, with one mechanism being the increased expression of ABC transporters (such as MDR1 and MRP1), which are drug efflux transporters capable of preventing intracellular accumulation of drugs and cell deat...

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Detalles Bibliográficos
Autores principales: Stefanski, Casey D., Arnason, Anne, Maloney, Sara, Kotsen, Janna, Powers, Elizabeth, Zhang, Jian-Ting, Prosperi, Jenifer R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145529/
https://www.ncbi.nlm.nih.gov/pubmed/37108784
http://dx.doi.org/10.3390/ijms24087621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145529/
https://www.ncbi.nlm.nih.gov/pubmed/37108784
http://dx.doi.org/10.3390/ijms24087621

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