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Platinum(IV)-Loaded Degraded Glycol Chitosan as Efficient Platinum(IV) Drug Delivery Platform

A new class of anticancer prodrugs was designed by combining the cytotoxicity of platinum(IV) complexes and the drug carrier properties of glycol chitosan polymers: Unsymmetrically carboxylated platinum(IV) analogues of cisplatin, carboplatin and oxaliplatin, namely (OC-6-44)-acetatodiammine(3-carbo...

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Detalles Bibliográficos
Autores principales: Lerchbammer-Kreith, Yvonne, Sommerfeld, Nadine S., Cseh, Klaudia, Weng-Jiang, Xian, Odunze, Uchechukwu, Schätzlein, Andreas G., Uchegbu, Ijeoma F., Galanski, Mathea S., Jakupec, Michael A., Keppler, Bernhard K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145531/
https://www.ncbi.nlm.nih.gov/pubmed/37111536
http://dx.doi.org/10.3390/pharmaceutics15041050