Cargando…

Platinum(IV)-Loaded Degraded Glycol Chitosan as Efficient Platinum(IV) Drug Delivery Platform

A new class of anticancer prodrugs was designed by combining the cytotoxicity of platinum(IV) complexes and the drug carrier properties of glycol chitosan polymers: Unsymmetrically carboxylated platinum(IV) analogues of cisplatin, carboplatin and oxaliplatin, namely (OC-6-44)-acetatodiammine(3-carbo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lerchbammer-Kreith, Yvonne, Sommerfeld, Nadine S., Cseh, Klaudia, Weng-Jiang, Xian, Odunze, Uchechukwu, Schätzlein, Andreas G., Uchegbu, Ijeoma F., Galanski, Mathea S., Jakupec, Michael A., Keppler, Bernhard K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145531/ https://www.ncbi.nlm.nih.gov/pubmed/37111536 http://dx.doi.org/10.3390/pharmaceutics15041050

Ejemplares similares

Quaternary Ammonium Palmitoyl Glycol Chitosan (GCPQ) Loaded with Platinum-Based Anticancer Agents—A Novel Polymer Formulation for Anticancer Therapy
por: Lerchbammer-Kreith, Yvonne, et al.
Publicado: (2023)

Combination of Drug Delivery Properties of PAMAM Dendrimers and Cytotoxicity of Platinum(IV) Complexes—A More Selective Anticancer Treatment?
por: Lerchbammer-Kreith, Yvonne, et al.
Publicado: (2023)

Diamminetetrakis(carboxylato)platinum(IV) Complexes – Synthesis, Characterization, and Cytotoxicity
por: Hoffmeister, Björn R, et al.
Publicado: (2012)

The impact of whole human blood on the kinetic inertness of platinum(iv) prodrugs – an HPLC-ICP-MS study
por: Theiner, Sarah, et al.
Publicado: (2018)

Synthesis and characterization of novel bis(carboxylato)dichloridobis(ethylamine)platinum(IV) complexes with higher cytotoxicity than cisplatin
por: Varbanov, Hristo, et al.
Publicado: (2011)

Unusual Enthalpy Driven Self Assembly at Room Temperature with Chitosan Amphiphiles
por: Odunze, Uchechukwu, et al.
Publicado: (2019)

Synthesis and Characterization of New Ethylenediamine Platinum(IV) Complexes Containing Lipophilic Carboxylate Ligands
por: Galanski, M., et al.
Publicado: (1995)

Theoretical Investigations and Density Functional Theory Based Quantitative Structure–Activity Relationships Model for Novel Cytotoxic Platinum(IV) Complexes
por: Varbanov, Hristo P., et al.
Publicado: (2012)

Multi-scale imaging of anticancer platinum(iv) compounds in murine tumor and kidney
por: Legin, A. A., et al.
Publicado: (2016)

Behavior of platinum(iv) complexes in models of tumor hypoxia: cytotoxicity, compound distribution and accumulation†
por: Schreiber-Brynzak, Ekaterina, et al.
Publicado: (2016)

NanoSIMS combined with fluorescence microscopy as a tool for subcellular imaging of isotopically labeled platinum-based anticancer drugs
por: Legin, Anton A., et al.
Publicado: (2014)

Amphotericin B Polymer Nanoparticles Show Efficacy against Candida Species Biofilms
por: Alakkad, Abdulghani, et al.
Publicado: (2022)

Synthesis and in vitro Antitumor Potency of (Cyclohexane-1,2-Diamine)Platinum(II) Complexes with Aminotris(Methylenephosphonic Acid) as Bone-Seeking Ligand
por: Galanski, Markus, et al.
Publicado: (2005)

Dibromidodimethyldipyridineplatinum(IV)
por: Kelly, Mairéad E., et al.
Publicado: (2008)

EGFR-targeting peptide-coupled platinum(IV) complexes
por: Mayr, Josef, et al.
Publicado: (2017)

Potent Chlorambucil-Platinum(IV) Prodrugs
por: Aputen, Angelico D., et al.
Publicado: (2022)

Tumor-targeted dual-action NSAID-platinum(iv) anticancer prodrugs
por: Kastner, Alexander, et al.
Publicado: (2023)

Polymeric Micelles for the Enhanced Deposition of Hydrophobic Drugs into Ocular Tissues, without Plasma Exposure
por: Uchegbu, Ijeoma F., et al.
Publicado: (2021)

A platinum(IV) prodrug strategy to overcome glutathione-based oxaliplatin resistance
por: Fronik, Philipp, et al.
Publicado: (2022)

Toxicity of platinum (IV) salts for cells of pulmonary origin.
por: Waters, M D, et al.
Publicado: (1975)

Epigenetic and antitumor effects of platinum(IV)-octanoato conjugates
por: Novohradsky, Vojtech, et al.
Publicado: (2017)

Ligand Evolution in the Photoactivatable Platinum(IV) Anticancer Prodrugs
por: Huang, Jingjing, et al.
Publicado: (2022)

Bioactive Platinum(IV) Complexes Incorporating Halogenated Phenylacetates
por: Aputen, Angelico D., et al.
Publicado: (2022)

Repurposing Platinum(IV) Prodrugs to Modulate Mitochondrial Metabolism
por: Zacharioudakis, Emmanouil, et al.
Publicado: (2023)

Albumin-targeting of an oxaliplatin-releasing platinum(iv) prodrug results in pronounced anticancer activity due to endocytotic drug uptake in vivo
por: Schueffl, Hemma, et al.
Publicado: (2021)

In Vitro Evaluation of Oxoplatin: An Oral Platinum(IV) Anticancer Agent
por: Olszewski, Ulrike, et al.
Publicado: (2009)

trans-Tetrachloridobis(diphenylacetonitrile)platinum(IV)
por: Bokach, Nadezhda A., et al.
Publicado: (2009)

Axial functionalisation of photoactive diazido platinum(iv) anticancer complexes
por: Shi, Huayun, et al.
Publicado: (2020)

Recovery of Palladium(II) and Platinum(IV) in Novel Extraction Systems
por: Wiecka, Zuzanna, et al.
Publicado: (2021)

Cyclooxygenase-Inhibiting Platinum(IV) Prodrugs with Potent Anticancer Activity
por: Khoury, Aleen, et al.
Publicado: (2022)

Cell-permeable lanthanide–platinum(iv) anti-cancer prodrugs
por: Yao, Kezi, et al.
Publicado: (2021)

Brain Gene Silencing with Cationic Amino-Capped Poly(ethylene glycol) Polyplexes
por: Alamoudi, Abdullah A., et al.
Publicado: (2022)

Biological activity of Pt(IV) prodrugs triggered by riboflavin-mediated bioorthogonal photocatalysis
por: Alonso-de Castro, Silvia, et al.
Publicado: (2018)

Comparison of the effects of the oral anticancer platinum(IV) complexes oxoplatin and metabolite cis-diammine-tetrachlorido-platinum(IV) on global gene expression of NCI-H526 cells
por: Olszewski, Ulrike, et al.
Publicado: (2011)

Nano-scale imaging of dual stable isotope labeled oxaliplatin in human colon cancer cells reveals the nucleolus as a putative node for therapeutic effect
por: Legin, Anton A., et al.
Publicado: (2020)

Potential Anticancer Activities and Catalytic Oxidation Efficiency of Platinum(IV) Complex
por: El-bendary, Mohamed M., et al.
Publicado: (2022)

The First Anticancer Tris(pyrazolyl)borate Molybdenum(IV) Complexes: Tested in Vitro and in Vivo—A Comparison of O,O‐, S,O‐, and N,N‐Chelate Effects
por: Berasaluce, Iker, et al.
Publicado: (2019)

Structure–Activity Relationships of Triple-Action Platinum(IV) Prodrugs with Albumin-Binding Properties and Immunomodulating Ligands
por: Fronik, Philipp, et al.
Publicado: (2021)

Lack of nephrotoxicity of oral ammine/amine platinum (IV) dicarboxylate complexes in rodents.
por: McKeage, M. J., et al.
Publicado: (1993)

(5,5′-Dimethyl-2,2′-bipyridine)iodidotrimethylplatinum(IV)
por: Lundvall, Fredrik, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_kv3cq7d1m9k3f1vmu6qdqsqavu