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Brain Region-Specific Differences in Amyloid-β Plaque Composition in 5XFAD Mice

Senile plaques consisting of amyloid-beta (Aβ) peptides are a major pathological hallmark of Alzheimer’s disease (AD). Aβ peptides are heterogeneous regarding the exact length of their amino- and carboxy-termini. Aβ1-40 and Aβ1-42 are often considered to represent canonical “full-length” Aβ species....

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Detalles Bibliográficos
Autores principales: Bader, Angelika Sabine, Gnädig, Marius-Uwe, Fricke, Merle, Büschgens, Luca, Berger, Lena Josefine, Klafki, Hans-Wolfgang, Meyer, Thomas, Jahn, Olaf, Weggen, Sascha, Wirths, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145597/
https://www.ncbi.nlm.nih.gov/pubmed/37109582
http://dx.doi.org/10.3390/life13041053