Modulation of the 5-Lipoxygenase Pathway by Chalcogen-Containing Inhibitors of Leukotriene A(4) Hydrolase

The 5-lipoxygenase (5-LOX) pathway gives rise to bioactive inflammatory lipid mediators, such as leukotrienes (LTs). 5-LOX carries out the oxygenation of arachidonic acid to the 5-hydroperoxy derivative and then to the leukotriene A(4) epoxide which is converted to a chemotactic leukotriene B(4) (LT...

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Detalles Bibliográficos
Autores principales: Teder, Tarvi, König, Stefanie, Singh, Rajkumar, Samuelsson, Bengt, Werz, Oliver, Garscha, Ulrike, Haeggström, Jesper Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145651/
https://www.ncbi.nlm.nih.gov/pubmed/37108702
http://dx.doi.org/10.3390/ijms24087539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145651/
https://www.ncbi.nlm.nih.gov/pubmed/37108702
http://dx.doi.org/10.3390/ijms24087539

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