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Valvular Cardiomyopathy in Aortic Valve Regurgitation Correlates with Myocardial Fibrosis

Objective: At the tissue level, disruption of the extracellular matrix network leads to irreversible cardiac fibrosis, which contributes to myocardial dysfunction. At the myocyte level, downregulation of beta-adrenoceptors (beta-AR) reduces adaptation to increased workload. The aim of our study was...

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Detalles Bibliográficos
Autores principales: Petersen, Johannes, Iqbal, Shahria, Gedeon, Naomi, Kloth, Benjamin, Pecha, Simon, Yildirim, Yalin, Eschenhagen, Thomas, Reichenspurner, Hermann, Christ, Torsten, Girdauskas, Evaldas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145654/
https://www.ncbi.nlm.nih.gov/pubmed/37109251
http://dx.doi.org/10.3390/jcm12082915