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Valvular Cardiomyopathy in Aortic Valve Regurgitation Correlates with Myocardial Fibrosis
Objective: At the tissue level, disruption of the extracellular matrix network leads to irreversible cardiac fibrosis, which contributes to myocardial dysfunction. At the myocyte level, downregulation of beta-adrenoceptors (beta-AR) reduces adaptation to increased workload. The aim of our study was...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145654/ https://www.ncbi.nlm.nih.gov/pubmed/37109251 http://dx.doi.org/10.3390/jcm12082915 |