Dihydromyricetin Modulates Nrf2 and NF-κB Crosstalk to Alleviate Methotrexate-Induced Lung Toxicity

Background: Methotrexate (MTX) is an effective anticancer, anti-inflammatory, and immunomodulatory agent. However, it induces a serious pneumonitis that leads to irreversible fibrotic lung damage. This study addresses the protective role of the natural flavonoid dihydromyricetin (DHM) against MTX-in...

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Detalles Bibliográficos
Autores principales: Matouk, Asmaa I., Awad, Eman M., El-Tahawy, Nashwa F. G., El-Sheikh, Azza A. K., Anter, Aliaa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145727/
https://www.ncbi.nlm.nih.gov/pubmed/37111238
http://dx.doi.org/10.3390/ph16040481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145727/
https://www.ncbi.nlm.nih.gov/pubmed/37111238
http://dx.doi.org/10.3390/ph16040481

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