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Core Structure–Activity Relationship Studies of 5,7,20-O-Trimethylsilybins in Prostate Cancer Cell Models

Silibinin, also known as silybin, is isolated from milk thistle (Silybum marianum). Silibinin has been demonstrated to be a good lead compound due to its potential to prevent and treat prostate cancer. Its moderate potency and poor pharmacokinetic profile hindered it from moving forward to therapeut...

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Detalles Bibliográficos
Autores principales: Wu, Sitong, Chen, Guanglin, Chen, Eva Y., Farshidpour, Leyla S., Zhang, Qiang, Wang, Guangdi, Chen, Qiao-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145751/
https://www.ncbi.nlm.nih.gov/pubmed/37111288
http://dx.doi.org/10.3390/ph16040531