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Core Structure–Activity Relationship Studies of 5,7,20-O-Trimethylsilybins in Prostate Cancer Cell Models
Silibinin, also known as silybin, is isolated from milk thistle (Silybum marianum). Silibinin has been demonstrated to be a good lead compound due to its potential to prevent and treat prostate cancer. Its moderate potency and poor pharmacokinetic profile hindered it from moving forward to therapeut...
Autores principales: | Wu, Sitong, Chen, Guanglin, Chen, Eva Y., Farshidpour, Leyla S., Zhang, Qiang, Wang, Guangdi, Chen, Qiao-Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145751/ https://www.ncbi.nlm.nih.gov/pubmed/37111288 http://dx.doi.org/10.3390/ph16040531 |
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