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Drug Repurposing of FDA Compounds against α-Glucosidase for the Treatment of Type 2 Diabetes: Insights from Molecular Docking and Molecular Dynamics Simulations

Type 2 diabetes mellitus is a chronic health problem that can be controlled by slowing one’s carbohydrate metabolism by inhibiting α-glucosidase, an enzyme responsible for carbohydrate degradation. Currently, drugs for type 2 diabetes have limitations in terms of safety, efficiency, and potency, whi...

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Detalles Bibliográficos
Autores principales: Rashid, Rebwar Saeed M., Temurlu, Selin, Abourajab, Arwa, Karsili, Pelin, Dinleyici, Meltem, Al-Khateeb, Basma, Icil, Huriye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145898/
https://www.ncbi.nlm.nih.gov/pubmed/37111312
http://dx.doi.org/10.3390/ph16040555