A cell-penetrating PHLPP peptide improves cardiac arrest survival in murine and swine models

Out-of-hospital cardiac arrest is a leading cause of death in the US, with a mortality rate over 90%. Preclinical studies demonstrate that cooling during cardiopulmonary resuscitation (CPR) is highly beneficial, but can be challenging to implement clinically. No medications exist for improving long-...

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Detalles Bibliográficos
Autores principales: Li, Jing, Zhu, Xiangdong, Oberdier, Matt T., Lee, Chunpei, Lin, Shaoxia, Fink, Sarah J., Justice, Cody N., Qin, Kevin, Begeman, Andrew W., Damen, Frederick C., Kim, Hajwa, Chen, Jiwang, Cai, Kejia, Halperin, Henry R., Vanden Hoek, Terry L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145924/
https://www.ncbi.nlm.nih.gov/pubmed/37115695
http://dx.doi.org/10.1172/JCI164283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145924/
https://www.ncbi.nlm.nih.gov/pubmed/37115695
http://dx.doi.org/10.1172/JCI164283

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