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Elevated prelimbic cortex-to-basolateral amygdala circuit activity mediates comorbid anxiety-like behaviors associated with chronic pain

Chronic pain can cause both hyperalgesia and anxiety symptoms. However, how the two components are encoded in the brain remains unclear. The prelimbic cortex (PrL), a critical brain region for both nociceptive and emotional modulations, serves as an ideal medium for comparing how the two components...

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Detalles Bibliográficos
Autores principales: Gao, Feng, Huang, Jie, Huang, Guo-Bin, You, Qiang-Long, Yao, Shan, Zhao, Shen-Ting, Liu, Jian, Wu, Cui-Hong, Chen, Gui-Fu, Liu, Shi-Min, Yu, Zongyan, Zhou, Yan-Ling, Ning, Yu-Ping, Liu, Shenquan, Hu, Bing-Jie, Sun, Xiang-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145931/
https://www.ncbi.nlm.nih.gov/pubmed/36917193
http://dx.doi.org/10.1172/JCI166356