An IGFBP7(hi) endothelial cell subset drives T cell extravasation in psoriasis via endothelial glycocalyx degradation

Dysfunction of vascular endothelial cells (ECs) facilitates imbalanced immune responses and tissue hyperinflammation. However, the heterogeneous functions of skin ECs and their underlying mechanism in dermatoses remain to be determined. Here, focusing on the pathogenic role of skin ECs in psoriasis,...

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Detalles Bibliográficos
Autores principales: Li, Qingyang, Shao, Shuai, Zhu, Zhenlai, Chen, Jiaoling, Hao, Junfeng, Bai, Yaxing, Li, Bing, Dang, Erle, Wang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145935/
https://www.ncbi.nlm.nih.gov/pubmed/36917196
http://dx.doi.org/10.1172/JCI160451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145935/
https://www.ncbi.nlm.nih.gov/pubmed/36917196
http://dx.doi.org/10.1172/JCI160451

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