Pressure overload induces ISG15 to facilitate adverse ventricular remodeling and promote heart failure

Inflammation promotes adverse ventricular remodeling, a common antecedent of heart failure. Here, we set out to determine how inflammatory cells affect cardiomyocytes in the remodeling heart. Pathogenic cardiac macrophages induced an IFN response in cardiomyocytes, characterized by upregulation of t...

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Detalles Bibliográficos
Autores principales: Yerra, Veera Ganesh, Batchu, Sri Nagarjun, Kaur, Harmandeep, Kabir, MD Golam, Liu, Youan, Advani, Suzanne L., Tran, Duc Tin, Sadeghian, Shadi, Sedrak, Phelopater, Billia, Filio, Kuzmanov, Uros, Gramolini, Anthony O., Qasrawi, Deema O., Petrotchenko, Evgeniy V., Borchers, Christoph H., Connelly, Kim A., Advani, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145941/
https://www.ncbi.nlm.nih.gov/pubmed/37115698
http://dx.doi.org/10.1172/JCI161453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145941/
https://www.ncbi.nlm.nih.gov/pubmed/37115698
http://dx.doi.org/10.1172/JCI161453

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