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Tgr5(−/−) mice are protected from ethanol-induced metabolic alterations through enhanced leptin and Fgf21 signaling

Alcohol-associated liver disease (ALD) is caused by chronic use of alcohol and ranges from hepatic steatosis to fibrosis and cirrhosis. Bile acids are physiological detergents that also regulate hepatic glucose and lipid homeostasis by binding to several receptors. One such receptor, Takeda G protei...

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Detalles Bibliográficos
Autores principales: Pokhrel, Sabita, Dilts, Matthew, Stahl, Zachary, Boehme, Shannon, Frame, Gabrielle, Chiang, John Y.L., Ferrell, Jessica M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145946/
https://www.ncbi.nlm.nih.gov/pubmed/37185802
http://dx.doi.org/10.1097/HC9.0000000000000138