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Tgr5(−/−) mice are protected from ethanol-induced metabolic alterations through enhanced leptin and Fgf21 signaling
Alcohol-associated liver disease (ALD) is caused by chronic use of alcohol and ranges from hepatic steatosis to fibrosis and cirrhosis. Bile acids are physiological detergents that also regulate hepatic glucose and lipid homeostasis by binding to several receptors. One such receptor, Takeda G protei...
Autores principales: | Pokhrel, Sabita, Dilts, Matthew, Stahl, Zachary, Boehme, Shannon, Frame, Gabrielle, Chiang, John Y.L., Ferrell, Jessica M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145946/ https://www.ncbi.nlm.nih.gov/pubmed/37185802 http://dx.doi.org/10.1097/HC9.0000000000000138 |
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