RIP140 deficiency enhances cardiac fuel metabolism and protects mice from heart failure

During the development of heart failure (HF), the capacity for cardiomyocyte (CM) fatty acid oxidation (FAO) and ATP production is progressively diminished, contributing to pathologic cardiac hypertrophy and contractile dysfunction. Receptor-interacting protein 140 (RIP140, encoded by Nrip1) has bee...

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Detalles Bibliográficos
Autores principales: Yamamoto, Tsunehisa, Maurya, Santosh K., Pruzinsky, Elizabeth, Batmanov, Kirill, Xiao, Yang, Sulon, Sarah M., Sakamoto, Tomoya, Wang, Yang, Lai, Ling, McDaid, Kendra S., Shewale, Swapnil V., Leone, Teresa C., Koves, Timothy R., Muoio, Deborah M., Dierickx, Pieterjan, Lazar, Mitchell A., Lewandowski, E. Douglas, Kelly, Daniel P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145947/
https://www.ncbi.nlm.nih.gov/pubmed/36927960
http://dx.doi.org/10.1172/JCI162309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145947/
https://www.ncbi.nlm.nih.gov/pubmed/36927960
http://dx.doi.org/10.1172/JCI162309

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