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Viral Protein VP1 Virus-like Particles (VLP) of CVB4 Induces Protective Immunity against Lethal Challenges with Diabetogenic E2 and Wild Type JBV Strains in Mice Model

Several epidemiological studies demonstrated that coxsackievirus B4 (CVB4) causes viral pancreatitis and can ultimately result in type 1 diabetes mellitus (T1D). Prevention of CVB4 infection is therefore highly desirable. There is currently no vaccine or antiviral therapeutic reagent in clinical use...

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Detalles Bibliográficos
Autores principales: Gharbi, Jawhar, Hadj Hassine, Ikbel, Hassine, Mouna, Al-Malki, Mohammed, Al-Yami, Ameera, Al-Bachir, Anwar, Ben M’hadheb, Manel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145976/
https://www.ncbi.nlm.nih.gov/pubmed/37112858
http://dx.doi.org/10.3390/v15040878