Multiple Strategies to Develop Small Molecular KRAS Directly Bound Inhibitors

KRAS gene mutation is widespread in tumors and plays an important role in various malignancies. Targeting KRAS mutations is regarded as the “holy grail” of targeted cancer therapies. Recently, multiple strategies, including covalent binding strategy, targeted protein degradation strategy, targeting...

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Detalles Bibliográficos
Autores principales: Zhou, Xile, Ji, Yang, Zhou, Jinming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146153/
https://www.ncbi.nlm.nih.gov/pubmed/37110848
http://dx.doi.org/10.3390/molecules28083615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146153/
https://www.ncbi.nlm.nih.gov/pubmed/37110848
http://dx.doi.org/10.3390/molecules28083615

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