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The 4-α-Glucanotransferase AcbQ Is Involved in Acarbose Modification in Actinoplanes sp. SE50/110

The pseudo-tetrasaccharide acarbose, produced by Actinoplanes sp. SE50/110, is a α-glucosidase inhibitor used for treatment of type 2 diabetes patients. In industrial production of acarbose, by-products play a relevant role that complicates the purification of the product and reduce yields. Here, we...

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Detalles Bibliográficos
Autores principales: Nölting, Sophia, März, Camilla, Jacob, Lucas, Persicke, Marcus, Schneiker-Bekel, Susanne, Kalinowski, Jörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146171/
https://www.ncbi.nlm.nih.gov/pubmed/37110271
http://dx.doi.org/10.3390/microorganisms11040848