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Control Analysis of Cooperativity and Complementarity in Metabolic Regulations: The Case of NADPH Homeostasis

Complex feedback regulation patterns shape the cellular metabolic response to external or internal perturbations. We propose here a framework consisting of a sampling-based metabolic control analysis of kinetic models to investigate the modes of regulatory interplay in metabolic functions. NADPH hom...

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Detalles Bibliográficos
Autores principales: Pfeuty, Benjamin, Hurbain, Julien, Thommen, Quentin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146214/
https://www.ncbi.nlm.nih.gov/pubmed/37110144
http://dx.doi.org/10.3390/metabo13040485