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The Role of C2 Domains in Two Different Phosphatases: PTEN and SHIP2

Phosphatase and tensin homologue (PTEN) and SH2-containing inositol 5′-phosphatase 2 (SHIP2) are structurally and functionally similar. They both consist of a phosphatase (Ptase) domain and an adjacent C2 domain, and both proteins dephosphorylate phosphoinositol-tri(3,4,5)phosphate, PI(3,4,5)P(3); P...

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Detalles Bibliográficos
Autores principales: John, Laura H., Naughton, Fiona B., Sansom, Mark S. P., Larsen, Andreas Haahr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146288/
https://www.ncbi.nlm.nih.gov/pubmed/37103835
http://dx.doi.org/10.3390/membranes13040408