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Sensing of Catecholamine in Human Urine Using a Simple Colorimetric Assay Based on Direct Melanochrome and Indolequinone Formation

We used the first enzyme-free synthesis and stabilization of soluble melanochrome (MC) and 5,6-indolequinone (IQ) derived from levodopa (LD), dopamine (DA), and norepinephrine (NE) oxidation to develop a simple colorimetric assay for catecholamine detection in human urine, also elucidating the time-...

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Detalles Bibliográficos
Autores principales: Lettieri, Mariagrazia, Spinelli, Michele, Caponi, Laura, Scarano, Simona, Palladino, Pasquale, Amoresano, Angela, Minunni, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146333/
https://www.ncbi.nlm.nih.gov/pubmed/37112313
http://dx.doi.org/10.3390/s23083971