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Microfluidic Bi-Layer Platform to Study Functional Interaction between Co-Cultured Neural Networks with Unidirectional Synaptic Connectivity

The complex synaptic connectivity architecture of neuronal networks underlies cognition and brain function. However, studying the spiking activity propagation and processing in heterogeneous networks in vivo poses significant challenges. In this study, we present a novel two-layer PDMS chip that fac...

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Detalles Bibliográficos
Autores principales: Pigareva, Yana, Gladkov, Arseniy, Kolpakov, Vladimir, Bukatin, Anton, Li, Sergei, Kazantsev, Victor B., Mukhina, Irina, Pimashkin, Alexey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146337/
https://www.ncbi.nlm.nih.gov/pubmed/37421068
http://dx.doi.org/10.3390/mi14040835