In Vitro High-Throughput Genotoxicity Testing Using γH2AX Biomarker, Microscopy and Reproducible Automatic Image Analysis in ImageJ—A Pilot Study with Valinomycin

(1) Background: The detection of DNA double-strand breaks in vitro using the phosphorylated histone biomarker (γH2AX) is an increasingly popular method of measuring in vitro genotoxicity, as it is sensitive, specific and suitable for high-throughput analysis. The γH2AX response is either detected by...

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Detalles Bibliográficos
Autores principales: Křížkovská, Bára, Schätz, Martin, Lipov, Jan, Viktorová, Jitka, Jablonská, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146355/
https://www.ncbi.nlm.nih.gov/pubmed/37104201
http://dx.doi.org/10.3390/toxins15040263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146355/
https://www.ncbi.nlm.nih.gov/pubmed/37104201
http://dx.doi.org/10.3390/toxins15040263

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